Papering the record for appeal.
A lighted sign displays the moderna logo above the main entrance to global headquarters for Moderna Therapeutics in Cambridge, Massachusetts. (Cambridge, MA)
¶I woke up a little early and went for a walk around the hotel. Looks like plenty of people were already at work at Moderna.
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¶Up and on the road early today - driving to Cambridge to pick Jonathan up from school.
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Pfizer and BioNTech request emergency authorization from FDA for Covid vaccine (cnbc.com)
¶And now the review....
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¶Jonathan called just as I caught that sunset photo on the turnpike. We decided to meet in Cambridge for dinner. We grabbed a pizza at Pinocchio’s, which has become his favorite pizza place at school, and headed down to the river. What a great time (and great pizza!). He’s incredibly happy, which, of course, makes me happy!
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¶Caught this sunset as I stopped for gas in Massachusetts. Insane light.
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¶I must be on the same cycle as the last trip to Boston - I remember stopping at this rest stop and thinking I should take a picture. This time I did.
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¶Lucas county issued a stay at home advisory for the next twenty-eight days. Not a lockdown, just an advisory. Seems like a good idea - hopefully it will reduce interactions and get our numbers down.
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Help is on its Way by Little River Band (apple.com)
¶Vaccine news has me singing “Help is on its Way” by Little River Band. Great song. “I’ll be there as fast as I can....”
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Pfizer says final data analysis shows Covid vaccine is 95% effective – plans to submit to FDA in ‘days’ (cnbc.com)
¶We’re about to start the next leg of this marathon - regulatory review.
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¶That feeling when you realize the sun, sky, wind, and water are going to cooperate!
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¶The tripod is set on a pile of logs and twigs that accumulates at the bend. Not exactly a comfortable position, but the angle was perfect.
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¶The sky even had just enough cloud cover to provide beautiful colors after the sun had set…and the river was calm enough to give a killer reflection.
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¶The trees split rays perfectly as the sun dropped behind them.
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¶I got in position just as the sun centered on the stretch of the river near Davis Overlook. Set up the tripod and took this shot straight away.
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¶Headed down to the river for the sunset tonight, and am glad I did - everything fell into place perfectly. Got some beautiful shots!
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¶…and it’s snowing....
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¶Testing new code for default publication date.
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Singapore biotech firm hopes for ‘widespread’ release of new Covid-19 treatment by early 2021 (cnbc.com)
¶We might find ourselves awash with vaccines and treatments for COVID-19 in early 2021. It’s possible that in the span of a year, the clinical challenge may have gone from not knowing how to treat the disease at all to not know which treatment is the best to use in a particular situation.
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Immunological memory to SARS-CoV-2 assessed for greater than six months after infection (biorxiv.org)
¶The memory component of the immune response to SARS CoV-2 is coming into focus. It appears to be a bit heterogenous, much like the initial response, but “immune memory consisting of at least three immunological compartments was measurable in ~90% of subjects > 5 months PSO, indicating that durable immunity against COVID-19 disease is a possibility in most individuals.”
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¶Six weeks after ordering it, our new refrigerator arrived today. Not sure why, but I’m sort of looking forward to organizing it.
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¶Our vagabond kitty returned tonight after a three day absence. He would have set a new record for days away had he not come tonight. And he was starving - scarfed down to cans of food in a matter of minutes! Renee and I were both happy to see him.
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‘We could effectively end this pandemic in 2021’ with Pfizer and Moderna Covid vaccines (cnbc.com)
¶Gottleib is a former FDA Commissioner, very cautious by nature, and on the Board at Pfizer. His statement this morning, following Moderna’s announcement, is significant.
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Moderna says preliminary trial data shows its coronavirus vaccine is more than 94% effective, shares soar (cnbc.com)
¶Science will win this thing.
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¶Preparations for the new puppy have officially begun. T-minus a week or so and counting.
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¶Sky looks better this morning…sunset might be a little more interesting tonight. Last night was a bust.
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