Chemistry textbooks have been getting this wrong for nearly 100 years (sciencedaily.com)
¶For decades, organic chemistry textbooks have generally taught that the influence of certain atoms can travel through three or four bonds within a molecule. According to the traditional explanation, that influence becomes progressively weaker as it moves farther from the original atom.
¶The researchers say the evidence paints a different picture.
¶“Instead, we show that the inductive effect in a neutral molecule does not extend beyond one bond. As a result of this, we need to refine explanations for certain types of reactivity. This can provide a more coherent framework for explaining chemical structure and reactivity.”
¶Rather than treating the inductive effect as an influence that gradually travels along a chain of atoms, the team’s interpretation confines it to the bond directly connected to the relevant atom in a neutral molecule.
¶Science is never written in stone, that’s part of its beauty.